Next generation sequencing in cancer research. Volume 1, Decoding the cancer genome (eBook, 2013) [WorldCat.org]
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Next generation sequencing in cancer research. Volume 1, Decoding the cancer genome

Author: Wei Wu, Dr.; Hani Choudhry
Publisher: New York, NY : Springer, ©2013.
Series: 2012-2013 Springer E-Books - Biomedical & Life Sciences.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Next Generation Sequencing (NGS) technology has placed important milestones in the life science and changed the direction in biomedical science inclucing cancer. Scientists around the world are attempting to find the root cause of cancer and they are looking for more direct and effective means to cure cancer. This journey to conquer cancer is more optimistic now with the unfolding of the cancer genome. This book  Read more...
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Details

Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Wei Wu, Dr.; Hani Choudhry
ISBN: 9781461476450 1461476453 1461476445 9781461476443
OCLC Number: 856631749
Language Note: English.
Description: 1 online resource (xxiii, 383 pages) : illustrations
Contents: The evolution of high-throughput sequencing technologies : from Sanger to single-molecule sequencing / Chee-Seng Ku, Yudi Pawitan, Mengchu Wu, Dimitrios H. Roukos, and David N. Cooper --
Next-generation sequencing in cancer epigenomics and potential clinical applications / Hong Kiat Ng, Dimitrios H. Roukos, Barry Iacopetta, and Chee-Seng Ku --
Next-generation sequencing for cancer genomics / Aarti N. Desai and Abhay Jere --
Genomic landscape of cancer metastasis / Arvind K. Singla, Chandini Thirukkumaran, Rajiv Dixit, and Wei Wu --
Mapping the HIF transcription factor in cancer by ChIP-seq technology / Johannes Schödel and David R. Mole --
Application of next-generation sequencing to analysis of TGFß/SMAD4 targets in ovarian cancer / Russell Bonneville, Kenneth Nephew, and Victor X. Jin --
Targeted sequencing strategies in cancer research / HoJoon Lee, Billy T. Lau, and Hanlee P. Ji --
Comprehensive genomic alterations in common cancer cell lines revealed by exome sequencing / Han Chang, Donald G. Jackson, Paul S. Kayne, Petra B. Ross-Macdonald, Rolf-Peter Ryseck, and Nathan O. Siemers --
Application of next-generation sequencing in RNA biomarker discovery in cancer research / Stephen P. Fink and Kishore Guda Understanding the role of long noncoding RNAs in the cancer genome / Wei Wu and Jennifer A. Chan --
Identification of piRNAs in HeLa cells by massive parallel sequencing / Yilu Lu and Yongxin Ma --
MicroRNA expression in breast cancer revealed by deep sequencing technology / Thalia A. Farazi, Carl S. Leonhardt, and Thomas Tuschl --
RNA-Seq in prostate cancer research / ShanCheng Ren, Min Qu, and Yinghao Sun --
Next-generation sequencing for high-throughput RNA interference screens / Toby M. Ward, Anna-Maria Jegg, and Elizabeth Iorns --
Assessment of mapping and SNP-detection algorithms for next-generation sequencing data in cancer genomics / Weixin Wang, Feng Xu, and Junwen Wang --
Applications of very low-coverage sequencing in cancer genomics : copy number, virus detection and survival / Henry M. Wood --
Tumor phylogenetics in the NGS era : strategies, challenges, and future prospects / Ayshwarya Subramanian, Stanley Shackney, and Russell Schwartz --
Impact and challenges in assessing tumor purity by next-generation sequencing / Xiaoping Su, Gabriel G. Malouf, and Francisco J. Esteva.
Series Title: 2012-2013 Springer E-Books - Biomedical & Life Sciences.
Other Titles: Decoding the cancer genome
Responsibility: Wei Wu, Hani Choudhry, Editors.

Abstract:

It aims to systematically introduce the concept of NGS, a variety of NGS platforms and their practical implications in cancer biology.This unique and comprehensive text will integrate the  Read more...

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